Glossary
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Сұрақ: (Соңғы өңдеу: )Citation amnesia | |||
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Жауап: failing to cite important work in the field in a paper, book, or presentation. | |||
Сұрақ: (Соңғы өңдеу: )Classified research | |||
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Жауап: research that the government keeps secret to protect national security. Access to classified research is granted to individuals with the appropriate security clearance on a need-to-know basis. | |||
Сұрақ: (Соңғы өңдеу: )Clinical investigator | |||
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Жауап: a researcher involved in conducting a clinical trial | |||
Сұрақ: (Соңғы өңдеу: )Clinical trial | |||
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Жауап: an experiment designed to test the safety or efficacy of a type of therapy (such as a drug). | |||
Сұрақ: (Соңғы өңдеу: )Clinical trial, active controlled | |||
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Жауап: a clinical trial in which the control group receives a treatment known to be effective. The goal of the trial is to compare different treatments. | |||
Сұрақ: (Соңғы өңдеу: )Clinical trial, phases | |||
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Жауап: sequential stages of clinical testing, required by regulatory agencies, used in the development of medical treatments. Pre-clinical testing involves experiments on animals or cells to estimate safety and potential efficacy. Phase I trials are small studies (50-100 subjects) conducted in human beings for the first time to assess safety, pharmacology, or dosing. Phase I studies are usually conducted on healthy volunteers though some are conducted on patients with terminal diseases, such as cancer patients. Phase II trials are larger studies (500 or more subjects) conducted on patients with a disease to assess safety and efficacy and establish a therapeutic dose. Phase III trials are large studies (up to several thousand subjects) conducted on patients to obtain more information on safety and efficacy. Phase IV (or post-marketing) studies are conducted after a treatment has been approved for marketing to gather more information on safety and efficacy and to expand the range of the population being treated. | |||
Сұрақ: (Соңғы өңдеу: )Clinical trial, placebo controlled | |||
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Жауап: a clinical trial in which the control group receives a placebo. The goal of the trial is to compare a treatment to a placebo. | |||
Сұрақ: (Соңғы өңдеу: )Clinical trial, registration | |||
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Жауап: providing information about a clinical trial in a public registry. Most journals and funding agencies require that clinical trials be registered. Registration information includes the name of the trial, the sponsor, study design and methods, population, inclusion/exclusion criteria, and outcome measures. | |||
Сұрақ: (Соңғы өңдеу: )Clinical utility | |||
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Жауап: the clinical usefulness of information, e.g. for making decisions concerning diagnosis, prevention, or treatment. | |||